Cho, Jaeheung

Cho, Jaeheung

Cho, Jaeheung 조재흥
Professor
RESEARCH AREA
Bioinspired Coordination Chemistry
Small Molecule Activation
CONTACT INFO

Research Summary
Our research program focuses on biomimetics in small molecule activation by using transition metal model complexes to understand biological systems and design emerging materials. The research requires the tools of chemical synthesis, physicochemical characterization, such as UV-vis, ESI-MS, rRaman, EPR, NMR and X-ray crystallography, and reactivity. It is a multidisciplinary field involving chemistry, biology, medicine, environmental science and others. The current goal of our research is divided into two categories: 1) drug development for anti tumor activity (e.g., anti cancer drug) and/or vasodilation (e.g., NO delivery); 2) green catalyst synthesis for sustainable environment (e.g., CO2 fixation) and energy conversion (e.g., C-H bond activation).

Representative Publications
Mechanistic insight into hydroxamate transfer reaction mimicking the inhibition of zinc-containing enzymes
N. Kwon, J. Suh, M. Lim, H. Hirao, J. Cho, Chem. Sci., 2020, 11, 9017
Artificial Control of Cell Signaling Using a Photocleavable Cobalt(III)–Nitrosyl Complex
Shin,‡ J. Choe,‡ Y. Park,‡ D. Jeong, H. Song, Y. You, D. Seo, J. Cho, Angew. Chem. Int. Ed., 2019, 58, 30, 10126
Structure and Reactivity of a Mononuclear Nonheme Manganese(III)-Idosylarene Complex
D. Jeong, T. Ohta, J. Cho, J. Am. Chem. Soc., 2018, 40, 47, 16037
Naphthalene Oxidation of a Manganese(IV)-Bis(Hydroxo) Complex in the Presence of Acid
D. Jeong, J. Yan, H. Noh, B. Hedman, K. Hodgson, E. Solomon, J. Cho, Angew. Chem. Int. Ed., 2018, 57, 26, 7764
Distinct Reactivity of a Mononuclear Peroxocobalt(III) Species towards Activation of Nitriles
H. Noh, D. Jeong, T. Ohta, T. Ogura, J. S. Valentine, J. Cho, J. Am. Chem. Soc., 2017, 139, 32, 10960