Membrane proteins play key roles in human health, contributing to cellular signaling, immunity, and material exchange. Additionally, this class of proteins is a major target for commercial drug molecules. We are therefore dedicated to unveiling their hidden dynamics using single-molecule tools and molecular dynamics simulation, which could contribute to the development of effective therapeutic interventions. Specifically, our focus is on understanding how membrane proteins fold into their native structures and how they interact with other proteins and biomolecules. We are also expanding our research scope to include fields such as protein oxidative damage and proteomics.